2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-148034
    Plm IV inhibitor-1
    		Inhibitor
    Plm IV inhibitor-1 (compound 6) is a potent plasmepsin IV (Plm IV) inhibitor with IC50s of 4.1, 0.80, 0.25, 0.35 µM for Plm I, Plm II, Plm IV, Cat D, respectively.
    Plm IV inhibitor-1
  • HY-17373S2
    Posaconazole-d3
    Posaconazole-d3 (SCH 56592-d3) is deuterium labeled Posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity.
    Posaconazole-d<sub>3</sub>
  • HY-N2899
    Arteannuin M
    Arteannuin M can be isolated from Artemisia annua, and can be used for anti-malarial research.
    Arteannuin M
  • HY-126914
    Diacetylcercosporin
    Diacetylcercosporin is a perylenequinone produced by Cercospora and Septoria that has diverse biological activities. Diacetylcercosporin inhibits the growth of P. falciparum strains that are sensitive and resistant to chloroquine (IC50s=2.75 and 1.94 μM for D6 and W2 clones, respectively) and L. donovani parasites (IC50=3.1 μM) in vitro. Diacetylcercosporin exhibits cytotoxicity against SK-MEL, KB, BT549, and SKOV3 human cancer cell lines (IC50s=4.8-8.7 μM). Diacetylcercosporin is also a phytotoxin that inhibits the growth of lettuce and bentgrass at a concentration of 1.62 mM.
    Diacetylcercosporin
  • HY-17595R
    Mebendazole (Standard)
    		Inhibitor
    Mebendazole (Standard) is the analytical standard of Mebendazole. This product is intended for research and analytical applications. Mebendazole is a highly effective, broad-spectrum antihelmintic against nematode infestations. Mebendazole also exhibits inhibitory effect against glioblastoma multiforme (GBM), inhibits Hedgehog pathway and tubulin polymerization. Mebendazole is orally active and can cross CNS penetration.
    Mebendazole (Standard)
  • HY-122406
    Thiacetarsamide
    		Inhibitor
    Thiacetarsamide is an adulticide. Thiacetarsamide shows inhibits for heartworm (Dirofilaria immitis).
    Thiacetarsamide
  • HY-105589
    Liroldine
    		Inhibitor
    Liroldine (Compound 10) is an anti-amebic agent that exhibits effective anti-amebic activity in both the intestines and livers of mice. Liroldine can be utilized for the research of amebiasis.
    Liroldine
  • HY-N5060S
    Estragole-d4
    Estragole-d4 is deuterated labeled S-Phenyl-d5-mercapturic Acid (HY-W654314). S-Phenyl is deuterated labeled S-Phenyl.
    Estragole-d<sub>4</sub>
  • HY-116870
    Vamidothion
    Vamidothion is a polar organophosphorus insecticide and acaricide with biological activity against insects and mites. Vamidothion is degraded by human serum albumin (HSA) and promotes adduct formation with tyrosine residues. The phosphate amino acid adducts formed after the reaction of vamidothion with HSA are detected by liquid chromatography quadrupole-Orbitrap mass spectrometry. The metabolites of vamidothion can be used in forensic toxicology to help determine deaths caused by organophosphorus poisoning.
    Vamidothion
  • HY-B0483R
    Tioxolone (Standard)
    		Inhibitor
    Tioxolone (Standard) is the analytical standard of Tioxolone. This product is intended for research and analytical applications. Tioxolone is an inhibitor for the carbonic anhydrase. Tioxolone exhibits anti-leishmanial, antitumor, and anti-inflammatory activities. Tioxolone can be used in research of acne and psoriasis.
    Tioxolone (Standard)
  • HY-W016586AR
    Acivicin hydrochloride (Standard)
    		Inhibitor
    Acivicin (hydrochloride) (Standard) is the analytical standard of Acivicin (hydrochloride). This product is intended for research and analytical applications. Acivicin hydrochloride (AT-125 hydrochloride), a natural product produced by Streptomyces sviceus, is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin hydrochloride can across the blood-brain barrier and has anti-cancer, anti-parasitic properties[1][2].
    Acivicin hydrochloride (Standard)
  • HY-13801R
    Fexinidazole (Standard)
    		Inhibitor
    Fexinidazole (Standard) is the analytical standard of Fexinidazole. This product is intended for research and analytical applications. Fexinidazole (HOE 239) is an orally active, potent nitroimidazole antitrypanosomal agent. Fexinidazole shows trypanocidal activity against T. brucei subspecies and strains with IC50s of 0.7-3.3 μM (0.2-0.9 μg/ml). Fexinidazol has the potential for human sleeping sickness (HAT) caused by infection with T. brucei.
    Fexinidazole (Standard)
  • HY-121157
    Chlorfenson
    		Inhibitor
    Chlorfenson is an acaricide.
    Chlorfenson
  • HY-17592R
    Bithionol (Standard)
    		Inhibitor
    Bithionol (Standard) is the analytical standard of Bithionol. This product is intended for research and analytical applications. Bithionol is an antibacterial, anthelmintic, and algaecide agent. Bithionol is also a potent inhibitor of soluble adenylyl cyclase through binding to the allosteric activator site (IC50: 4 μM).
    Bithionol (Standard)
  • HY-12651R
    Primaquine (diphosphate) (Standard)
    		Inhibitor
    Primaquine (diphosphate) (Standard) is the analytical standard of Primaquine (diphosphate). This product is intended for research and analytical applications. Primaquine diphosphate is a potent antimalaria agent and a potent gametocytocide in falciparum malaria. Primaquine diphosphate prevents relapse in vivax and ovale malaria.
    Primaquine (diphosphate) (Standard)
  • HY-B1336R
    Furazolidone (Standard)
    Furazolidone (Standard) is the analytical standard of Furazolidone. This product is intended for research and analytical applications. Furazolidone is a nitrofuran derivative with antiprotozoal and antibacterial activity. It inhibits AML1-ETO transformed cells with an IC50 of 12.7 μM.
    Furazolidone (Standard)
  • HY-116900
    Karsil
    Karsil serves as an agricultural pesticide.
    Karsil
  • HY-15310R
    Ivermectin (Standard)
    		Inhibitor
    Ivermectin (Standard) is the analytical standard of Ivermectin. This product is intended for research and analytical applications. Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin (MK-933) is a specific inhibitor of Impα/β1-mediated nuclear import and has potent antiviral activity towards both HIV-1 and dengue virus. It is a positive allosteric effector of P2X4 and the α7 neuronal nicotinic acetylcholine receptor (nAChRs). Ivermectin also inhibits bovine herpesvirus1 (BoHV-1) replication and inhibits BoHV-1 DNA polymerase nuclear import. Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19.
    Ivermectin (Standard)
  • HY-122522
    2-Methylcardol triene
    2-Methylcardol triene is a phenol found in cashew nut shell liquid that inhibits α-glucosidase (IC50=39.6 μM). 2-Methylcardol triene is schistosomicidal, killing 100% of adult S. mansoni worms after 24 hours when used at concentrations of 100 and 200 μM. 2-Methylcardol triene has been used as a starting material for the synthesis of mono- and bis-benzoxazines.
    2-Methylcardol triene
  • HY-136429AR
    Ethylhydrocupreine (hydrochloride) (Standard)
    		Inhibitor
    Ethylhydrocupreine (hydrochloride) (Standard) is the analytical standard of Ethylhydrocupreine (hydrochloride). This product is intended for research and analytical applications. Ethylhydrocupreine hydrochloride (Optochin hydrochloride) is a quinine derivate with antimicrobial activity against S. pneumoniae. Ethylhydrocupreine hydrochloride also possesses antimalarial activity against Plasmodium falciparum, with an IC50 of 25.75 nM. Ethylhydrocupreine hydrochloride is a Gallus gallus taste 2 receptors (ggTas2r1, ggTas2r2 and ggTas2r7) agonist.
    Ethylhydrocupreine (hydrochloride) (Standard)
Parasite Isoform Comparison

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